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» A TV Show on RNAi by PBS 
NOVA scienceNOW TV program describes RNAi as a major breakthrough in gene therapy with enormous medical promise. Provides basic overview of RNAi technology, current therapeutic approaches, and interview with the experts in the field. Includes 15-minutes T
http://www.pbs.org/wgbh/nova/sciencenow/3210/02.html
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» Article on RNAi by GNN
Online article describing gene silencing mechanism and how RNAi can be used for HIV treatment.
http://www.genomenewsnetwork.org/articles/06_02/hiv.shtml
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» Article on RNAi by HOPES
Online article describes basic mechanism of RNAi and how it can be applied for Huntington's disease treatment.
http://www.stanford.edu/group/hopes/treatmts/pbuildup/h2.html
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» Article on siRNA from Wikipedia
Describes small interfering RNA (siRNA) function, structure, use in research, and potential application for therapy.
http://en.wikipedia.org/wiki/Small_interfering_RNA
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» Cambridge Healthtech Institute
CHI organizes RNAi-related conferences throughout the US and Europe, including therapeutics, pharmaceutics, drug development, target discovery, and biodefense. Provides biotechnology news and conferences information.
http://www.healthtech.com/
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» CnidBase: Cnidarian Evolutionary Genomics Database
Cnidbase provides tools for researchers interested in studying gene expression of these organisms. Provides sequence BLAST tools, keyword search of genes and homologs, a literature scan, and several useful links.
http://cnidbase.bu.edu/
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» Drosophila RNAi Resource
Informational RNAi resource on studying drosophila genes and their roles in development by Society for Developmental Biology.
http://www.sdbonline.org/fly/aignfam/rnaistuf.htm
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» Focus Areas: RNAi from Invitrogen
Educational and product support page. Includes RNAi overview, history, and research suggestions for gene silencing experiments.
http://www.invitrogen.com/content.cfm?pageid=10062
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» Gene Silencing Mechanism
Animation of post transcriptional gene silencing or RNA Interference (RNAi) by Nature Reviews Genetics.
http://www.nature.com/nrg/journal/v2/n2/animation/nrg0201_110a_swf_MEDIA1.html
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» Genetic Diversity
Provides educational modules covering such parts of biology as genetics, cell biology, and gene expression.
http://genetics.nbii.gov
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» InFocus RNAi Web Broadcast by Bio.com
Review of RNAi advances, technologies and applications. Bio.com provides an online RNAi technology-focused webcast, experts in the field discuss new insights into the regulation of gene expression by RNAi.
http://www.bio.com/newsfeatures/infocus.jhtml?infocusId=1200002&realmId=
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» Journal of RNAi and Gene Silencing
Publishes peer-reviewed articles addressing the biology and application of RNA interference and gene silencing. Includes information about journal aims and scope, publication policies, and manuscript submission. Provides online access to journal articles.
http://www.libpubmedia.co.uk/RNAiJ/RNAiJHome.htm
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» MicroRNA in Cancer
Review of microRNA role in cancer by Nature journal. Provides full-length research papers and reviews.
http://www.nature.com/nature/journal/v435/n7043/edsumm/e050609-16.html
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» NANOPOLIS
Educational portal providing nanotechnology articles and multimedia courses in the multidisciplinary research areas.
http://www.nanopolis.net
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» Nature web focus: RNAi
Online review of RNA Interference biological phenomena. Includes citations of recent research publications, RNAi animations, and science news articles.
http://www.nature.com/nature/focus/rnai/index.html
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» Navigating Journey of Genome to Medicine
Review article on RNAi by International Herald Tribune. Provides an overview on RNA Interference discovery, current research efforts, and therapeutic potential.
http://www.iht.com/articles/2005/06/22/news/snturn.php
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» Oligoengine
Oligonucleotide design software for applications such as RNAi, DNA methylation, antisense, and genome arrays.
http://www.oligoengine.com
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» Oligonucleotide Therapeutic Society
Society host conferences on academia and industry-based research and development of oligonucleotide therapeutics: RNAi, antisense, and others. Provides society overview, publication materials, meetings, and contact information.
http://www.myots.org/
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» Ordway Research Institute
Not-for-profit corporation with a mission to translate basic science observations into therapeutics. Provides research services including quantitation of endogenous levels of microRNAs and mRNAs from experimental samples. Includes information on research
http://www.ordwayresearch.org
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» Pharmaceutical Discovery
Peer-review online journal publishing articles on recent advances in life sciences research and drug discovery. Includes RNAi related news, overview of new technology, and research articles.
http://www.pharmaceuticaldiscovery.com/
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» Protein Lounge
Provides database that contains targets against mRNA sequences throughout a variety of organisms. Includes gene search option, and disease-specific siRNA genes.
http://www.proteinlounge.com/sirna_home.asp
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» RNA Interference
Interactive online resource from Howard Hughes Medical Institute. Presents RNAi mechanism and overview of key scientific findings.
http://hhmi.org/biointeractive/rna/rnai/
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» RNA Interference at Journal Nature
Focus RNA Interference - online resource publishing recent advances in RNAi field, and novel applications in Nature Cell Biology and Nature Reviews.
http://www.nature.com/focus/rnai/
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» RNAi BioForum
Online forum for siRNA, microRNA and RNAi methods discussion.
http://www.protocol-online.org/forums/index.php?showforum=21
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» RNAi Database
Includes all siRNA from C. elegans including assay, resulting phenotypes, dsRNA target location. Database provides Gene/Protein or Phenotype search options.
http://www.rnai.org/
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» RNAi Gateway
Web resource from BioMed Central. Provides RNA Interference (RNAi) research highlights, journal links, news, and meeting information.
http://www.biomedcentral.com/gateways/RNAi/
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» RNAi News
Online resource for scientists, researchers, technologists, and executives engaged in RNA Interference, functional genomics, and drug discovery. Offers industry news, product reviews, and meetings information.
http://www.rnainews.com
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» RNAi Research and Therapeutics Conference
Meeting organized by GTCbio with main focus on RNA Interference. Purpose of the conference is to facilitate the exchange of biopharmaceutical and biomedical intelligence between industry leaders, academic and government organizations, and the financial co
http://gtcbio.com/confpage.asp?cid=21
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» RNAi Resource at Ambion
Online RNA Interference (RNAi) resource. Provide scientific and technical support, information on microRNA and small interfering RNA application in gene expression research.
http://www.ambion.com/techlib/resources/RNAi/
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» RNAi Resource at Macalester College
Informational resource, including RNAi mechanism, overview of current studies, and related research protocols.
http://www.macalester.edu/~montgomery/RNAi.html
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» RNAi Therapeutics: How Likely, How Soon?
Review article from PLoS Biology journal. Describes mechanism of RNA Interference, potential applications towards therapeutics, and current problems associated with delivery.
http://biology.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pbio.0020028
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» RNAi Transfection Resource
Review of transfection techniques such as electroporation, denrimers and lipids that are used for transfection of DNA, RNA, and siRNA. Includes information on optimized cell type specific transfection systems.
http://cell-transfection.blogspot.com/
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» RNAi.net
Online resource offering information RNA interference and related issues: news, interviews, articles, techniques.
http://www.rnai.net
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» RNAi@elegansNet
Directory on gene silencing by RNA interference (RNAi) literature and resources.
http://c.elegans.tripod.com/RNAi.htm
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» Rosetta Genomics
Israel-based microRNA genomics company, develops bioinformatic tools for miRNA gene detection approach.
http://www.rosettagenomics.com/
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» SBS Conference
The Society for Biomolecular Screening holds a conference on high-throughput RNAi screening approach using siRNA/shRNA libraries on September 11-15, 2005.
http://www.sbsonline.org/sbscon/2005/index.php
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» SI RNA - Small Interference RNA Resources
Online resource from Ion Channel Media Group. Provides news, publication links, and citations of the recent literature relevant to RNA Interference research.
http://www.si-rna.com
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» Second Annual Meeting of the Oligonucleotide Therapeutics Society
Yearly conference organized by New York Academy of Sciences. Scientists from industry and academia meet to discuss use of oligonucleotide-based gene-silencing techniques for development of innovative therapeutics. Includes information about conference reg
http://www.nyas.org/events/eventDetail.asp?eventID=5753&date=10/19/2006
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» Silencing Genomes
Portal about genome-wide applications of RNAi by Cold Spring Harbor Laboratory.
http://silencinggenomes.org/
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» Small RNAs: Delivering the future
Article by journal Nature about development of RNAi therapeutics.
http://www.nature.com/nature/journal/v450/n7172/full/4501117a.html
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» TargetScan
Online software provided by MIT for prediction of microRNA targets. Provides research data and online software for microRNA target identification and analysis.
http://genes.mit.edu/targetscan/
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» The RNAi Cure
A NOVA ScienceNOW science program by PBS feature the possible applications for RNAi therapy. Provides animations of key biological processes and mechanism of RNA Interference.
http://www.pbs.org/wgbh/nova/sciencenow/3210/02-cure.html
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» The RNAi Web
Online resource for RNA Interference (RNAi) technology. Offers overview of technology, references, and links on other RNAi-related web resources.
http://www.rnaiweb.com/
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» The RNAi vs. HIV
Reviews the use of this therapy in fighting HIV. Includes mechanism, difficulties, terms, and featured experiments.
http://myweb.dal.ca/tbaptist/rnai/
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» The microRNA Registry
Online resource provides a service for the assignment of miRNA gene names. Provides searchable database of published miRNA sequences. Includes data and research application information.
http://www.sanger.ac.uk/Software/Rfam/mirna/
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» The siRNA User Guide
Online guide for performing RNAi experiments using synthetic siRNA molecules. By Tuschl Lab at Rockefeller University.
http://www.rockefeller.edu/labheads/tuschl/sirna.html
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» Transcriptional Gene Silencing
Mechanisms of TGS by Kevin Morris laboratory. Includes description of HIV research performed using lentiviral vector gene therapy and RNAi mediated gene silencing.
http://www.scripps.edu/mem/rheum/morris/tgs/
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» Wikipedia Article on RNAi
Online article describing the basics of RNA Interference (RNAi) mechanism.
http://en.wikipedia.org/wiki/RNA_interference
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» microRNA and Cancer Therapeutics
Online review of microRNA application for potential therapy of cancer by Dmitriy Ovcharenko.
https://webspace.utexas.edu/do376/index.html
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